LightMIS: Ultra-Lightweight Medical Image Segmentation Without a Stage-Wise Decoder

Andrei Arhire, Mihaela-Elena Breabăn, Radu Timofte

Alexandru Ioan Cuza University of Iasi · University of Wurzburg

Published September 24, 2026 · on the feed September 28, 2026 · ▲ 10 · arXiv 2609.28327

Vision & multimodalScience & medicine Code arXiv ↗Hugging Face ↗

The abstract

We present LightMIS, a scalable family of ultra-lightweight convolutional networks for 2D binary medical image segmentation without a learned stage-wise decoder. LightMIS aligns the outputs of a five-level encoder to a common resolution using Scale-Aligned Projection blocks, aggregates them once, and refines the fused representation with an Adaptive Fusion Cascade. The cascade combines Adaptive Kernel Fusion with the proposed Progressive Receptive Fusion module, which uses temporary channel expansion, complementary depthwise receptive fields, and progressive cross-branch information transfer. We evaluate LightMIS-T, LightMIS-S, and LightMIS using five-fold cross-validation under a common nnU-Net v2.3.1 protocol on DRIVE, Kvasir-SEG, DSB18, BUSI, ISIC-2017, and ISIC-2018. Full LightMIS contains 0.131 M parameters and requires 0.575 GFLOPs for a 3times256times256 input, achieving modality-macro Dice and IoU scores of 86.71% and 78.99%, respectively. Mobile U-ViT obtains 86.75% Dice and 79.07% IoU, so the observed differences are 0.04 and 0.08 percentage points. Relative to Mobile U-ViT, nnWNet, and nnU-Net, LightMIS reduces parameter count by 90.58-99.61% and GFLOPs by 82.54-96.14%. On an Arm Mali-G52 MC2 GPU, all LightMIS variants achieve full GPU delegation, with median delegated latency ranging from 53.31 ms for LightMIS-T to 138.31 ms for LightMIS. These results demonstrate a favorable accuracy-complexity trade-off and on-device execution feasibility for the evaluated tasks. The code is publicly available at https://github.com/AndreiiArhire/LightMIS.

The Brief

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Transcript

LightMIS. Ultra-Lightweight Medical Image Segmentation Without a Stage-Wise Decoder. By Andrei Arhire and two others, from Alexandru Ioan Cuza University of Iasi and the University of Wurzburg. Published on the twenty-fourth of September. Its code repository is public and real: about twenty source files.

The task is two-dimensional binary medical image segmentation: marking, pixel by pixel, which part of an image is the structure of interest and which is not. The paper's target is doing this with networks that are ultra-lightweight, light enough to execute on the device itself, without giving up accuracy against larger models. Its title names the component it gives up to get there: a learned stage-wise decoder.

LightMIS is a scalable family of convolutional networks built around that omission. Instead of decoding stage by stage, it brings all of the encoder's outputs to the same resolution, combines them once, and spends its effort refining that single fused representation.

Concretely, the encoder has five levels. Scale-Aligned Projection blocks align the outputs of all five to a common resolution, and they are aggregated in one step. An Adaptive Fusion Cascade then refines the fused result. The cascade combines Adaptive Kernel Fusion with a newly proposed Progressive Receptive Fusion module, which uses temporary channel expansion, complementary depthwise receptive fields, and progressive information transfer across branches.

Three sizes are evaluated: LightMIS-T, LightMIS-S, and full LightMIS. Testing uses five-fold cross-validation under a common nnU-Net protocol, on six datasets: DRIVE, Kvasir-SEG, DSB18, BUSI, ISIC-2017, and ISIC-2018. Full LightMIS has zero point one three one million parameters and needs zero point five seven five GFLOPs for a two hundred and fifty-six pixel square image.

Averaged across modalities, it reaches a Dice score of eighty-six point seven one percent and an IoU of seventy-eight point nine nine percent. Mobile U-ViT obtains eighty-six point seven five Dice and seventy-nine point zero seven IoU, so the gaps are four hundredths and eight hundredths of a percentage point.

Against Mobile U-ViT, nnWNet, and nnU-Net, LightMIS cuts parameter count by between ninety point five eight and ninety-nine point six one percent, and GFLOPs by between eighty-two point five four and ninety-six point one four percent. On an Arm Mali-G52 MC2 GPU, every variant runs with full GPU delegation. Median delegated latency ranges from fifty-three point three one milliseconds for LightMIS-T to one hundred and thirty-eight point three one milliseconds for full LightMIS.

The authors frame the result as a favorable trade between accuracy and complexity, with on-device execution shown to be feasible for the tasks they evaluated. Dropping the stage-wise decoder costs a few hundredths of a point of Dice, and removes most of the parameters and computation.

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Chapter 1 🧩 · The problem

A segmentation model has to fit on a phone. Something big has to go.

You need to mark, pixel by pixel, the lesion or vessel in a medical image, and the model must run on an ordinary phone's GPU.

The road ahead

  1. 1 · The problem ~7 min Marking a lesion or vessel pixel by pixel on a phone's GPU is hard, because the usual U-shaped network spends much of its cost on its decoder.
  2. 2 · What came before ~3 min
  3. 3 · The key idea ~8 min Skip the stage-by-stage decoder: bring all five encoder levels to one resolution, merge them once, and spend the saved effort refining that merged map.
  4. 4 · Choose your own research ~3 min
  5. 5 · Build the method ~8 min The image is encoded at five levels, every level is aligned to one resolution, the aligned maps are merged once, and a cascade refines the result.
  6. 6 · The experiment ~6 min You’ll guess: With a small fraction of the parameters, how did LightMIS's averaged Dice score compare with that of the larger Mobile U-ViT?
  7. 7 · The viva ~5 min Three questions from the examiners, answered in your own words. Win it for the paper’s trophy.
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